protein

RIG-I

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RIG-I: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

10Connections

0Hypotheses

0Analyses

7Outgoing

3Incoming

0Experiments

0Debates

Summary

Page for RIG-I Protein

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🔬 Protein Info

Gene Symbol	RIG
Function	Rig I Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
Subcellular Localization	to Cytoplasm and plays a significant role in the pathogenesis of [Alzheimer's Di
GeneCards	RIG
Human Protein Atlas	RIG
Interactions	STING, TBK1, WAS
KG Connections	10 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

RIG-I Protein

protein · 576 words

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Pathway Diagram

flowchart TD
    RIG_I(["RIG-I"])
    FUS(["FUS"])
    STING(["STING"])
    TBK1(["TBK1"])
    WAS(["WAS"])
    Neuron["Neuron"]
    NEURON(["NEURON"])
    Neurodegeneration["Neurodegeneration"]

    FUS -->|"upstream of"| RIG_I
    RIG_I -->|"activates"| STING
    RIG_I -->|"activates"| TBK1
    RIG_I -->|"activates"| WAS
    RIG_I -->|"activates"| Neuron
    NEURON -->|"co discussed"| RIG_I
    Neurodegeneration -->|"activates"| RIG_I

    style RIG_I fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff

Outgoing (7)

Target	Relation	Type	Str
neurodegeneration	regulates	disease	0.55
neuroinflammation	regulates	disease	0.55
oxidative stress response	participates_in	pathway	0.55
Neuron	activates	cell_type	0.50
STING	activates	gene	0.50
TBK1	activates	gene	0.50
WAS	activates	protein	0.50

Incoming (3)

Source	Relation	Type	Str
FUS	upstream_of	protein	0.60
NEURON	co_discussed	gene	0.50
Neurodegeneration	activates	disease	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning RIG-I in their description or question text

No additional research found