protein

RAB3CPROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RAB3CPROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Rab3C Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.

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🔬 Protein Info

Gene Symbol	RAB3CPROTEIN
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	neuronal and neuroendocrine tissues, where it plays essential roles in regulated secretion, synaptic vesicle trafficking, and neurotransmitter release
Subcellular Localization	** \| Synaptic vesicles, secretory granules, plasma membrane \|
Molecular Weight	30 kDa
GeneCards	RAB3CPROTEIN
Human Protein Atlas	RAB3CPROTEIN
GTP-binding domain	Conserved GxxxxGKST motif for nucleotide binding
Switch I region	Conformational change upon GTP/GDP exchange
Switch II region	Effector interaction site
Hypervariable C-terminal region	Determines subcellular targeting
C CAAX motif	Prenylation site for membrane anchoring
GTPase-activating proteins (GAPs)	Accelerate GTP hydrolysis
Rabphilin-3A	Calcium-binding protein that links RAB3 to the release machinery
RIM (Rab3-interacting molecule)	Scaffold protein for active zone organization
Associated Diseases	Als
Interactions	ATP, Il-6, Stat3
KG Connections	29 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

rab3c Protein

protein · 964 words

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Pathway Diagram

graph TD
    RAB3CPROTEIN["RAB3CPROTEIN"]
    neurodegeneration["neurodegeneration"]
    RAB3CPROTEIN -->|"implicated_in"| neurodegeneration
    style RAB3CPROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning RAB3CPROTEIN in their description or question text

No additional research found