Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Paxalisib: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| PI3K/Akt/mTOR | inhibits | pathway | 0.95 |
| MTOR | inhibits | protein | 0.90 |
| PIK3CA | inhibits | gene | 0.90 |
| Systemic Glucose Feedback | causes | process | 0.85 |
| Diffuse Intrinsic Pontine Glioma | treats | disease | 0.85 |
| Insulin Levels | upregulates | biomarker | 0.85 |
| PKC Signaling | upregulates | pathway | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Enzastaurin | interacts_with | drug | 0.85 |
| Mt-125 | associated_with | drug | 0.85 |
| Radiotherapy | interacts_with | process | 0.75 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning Paxalisib in their description or question text
No additional research found