gene

PSD3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PSD3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

Summary

PSD3 (Phosphatidylserine Decarboxylase 3) - postsynaptic density protein involved in synaptic structure and function. Associated with schizophrenia and cognitive disorders.

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	PSD3
Aliases	Phosphatidylserine Decarboxylase 3
Function	is a postsynaptic density protein that plays critical roles in synaptic structure, function, and plasticity.
Amino Acids	755 aa
GeneCards	PSD3
Human Protein Atlas	PSD3
N-terminal PDZ domain	Binds to postsynaptic density proteins and ion channels
SH3 domain	Mediates protein-protein interactions with proline-rich motifs
GK domain	Catalytic domain involved in membrane association
C-terminal domain	Regulatory region for protein interactions
Receptor clustering	Helps organize AMPA and NMDA receptors at synapses
Signaling complex assembly	Brings together signaling molecules for efficient transduction
Cytoskeletal linkage	Connects postsynaptic proteins to the actin cytoskeleton
Synaptic plasticity	Regulates activity-dependent changes in synaptic strength
Long-term potentiation (LTP)	PSD3 levels increase during LTP, facilitating synaptic strengthening
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

PSD3 Gene

gene · 1807 words

→

Pathway Diagram

graph TD
    PSD3["PSD3"]
    neurodegeneration["neurodegeneration"]
    PSD3 -->|"implicated_in"| neurodegeneration
    style PSD3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning PSD3 in their description or question text

No additional research found