| Gene Symbol | PSD3 |
| Aliases | Phosphatidylserine Decarboxylase 3 |
| Function | is a postsynaptic density protein that plays critical roles in synaptic structure, function, and plasticity. |
| Amino Acids | 755 aa |
| GeneCards | PSD3 |
| Human Protein Atlas | PSD3 |
| N-terminal PDZ domain | Binds to postsynaptic density proteins and ion channels |
| SH3 domain | Mediates protein-protein interactions with proline-rich motifs |
| GK domain | Catalytic domain involved in membrane association |
| C-terminal domain | Regulatory region for protein interactions |
| Receptor clustering | Helps organize AMPA and NMDA receptors at synapses |
| Signaling complex assembly | Brings together signaling molecules for efficient transduction |
| Cytoskeletal linkage | Connects postsynaptic proteins to the actin cytoskeleton |
| Synaptic plasticity | Regulates activity-dependent changes in synaptic strength |
| Long-term potentiation (LTP) | PSD3 levels increase during LTP, facilitating synaptic strengthening |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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