gene

PSD2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PSD2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

Summary

Page for PSD2 Gene

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	Phosphatidylserine Decarboxylase
Chromosome	5q14.3
Protein Type	Enzyme
Function	is a crucial enzyme in phospholipid metabolism.
Primary Expression	Brain, liver, testis, widespread
Subcellular Localization	PSD2 has a distinctive subcellular distribution:
Molecular Weight	46 kDa
UniProt ID	Q8N5L0
NCBI Gene ID	151742
Ensembl ID	ENSG00000146054
OMIM	612596
Endoplasmic reticulum (ER)	Primary site of phosphatidylserine synthesis and PSD2 function
Mitochondrial membrane	PSD2 is also associated with mitochondrial membranes where it contributes to mitochondrial phospholipid composition
Golgi apparatus	Some PSD2 activity detected in Golgi membranes
Synaptic vesicles	Presence in synaptic vesicles suggests roles in neurotransmitter release
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: PSD2 — AlphaFold Q8N5L0 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

PSD2 Gene

gene · 1667 words

→

Pathway Diagram

graph TD
    PSD2["PSD2"]
    neurodegeneration["neurodegeneration"]
    PSD2 -->|"implicated_in"| neurodegeneration
    style PSD2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning PSD2 in their description or question text

No additional research found