gene 1,667 words KG: PSD2
Contents

PSD2 Gene

🧬 Gene Info
Gene SymbolPhosphatidylserine Decarboxylase
Chromosome5q14.3
Protein TypeEnzyme
Functionis a crucial enzyme in phospholipid metabolism.
Primary ExpressionBrain, liver, testis, widespread
Subcellular LocalizationPSD2 has a distinctive subcellular distribution:
Molecular Weight46 kDa
UniProt IDQ8N5L0
NCBI Gene ID151742
Ensembl IDENSG00000146054
OMIM612596
Endoplasmic reticulum (ER)Primary site of phosphatidylserine synthesis and PSD2 function
Mitochondrial membranePSD2 is also associated with mitochondrial membranes where it contributes to mitochondrial phospholipid composition
Golgi apparatusSome PSD2 activity detected in Golgi membranes
Synaptic vesiclesPresence in synaptic vesicles suggests roles in neurotransmitter release
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

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