Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PRMT: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | PRMT |
| Linked Hypotheses | 2 hypotheses |
Knowledge base pages for this entity
graph TD
PRMT["PRMT"]
PRMT -->|"regulates"| Transcription["Transcription"]
PRMT -->|"regulates"| RNA_Splicing["RNA Splicing"]
PRMT -->|"regulates"| DNA_Damage_Response["DNA Damage Response"]
PRMT -->|"regulates"| Cell_Metabolism["Cell Metabolism"]
PRMT -->|"involved_in"| Anti_Cancer_Drug_Resistance["Anti-Cancer Drug Resistance"]
PRMT -->|"promotes"| Drug_Resistance["Drug Resistance"]
PRMT -->|"promotes"| Drug_Tolerant_Cells["Drug-Tolerant Cells"]
PRMT -->|"regulates"| Immune_Cells["Immune Cells"]| Target | Relation | Type | Str |
|---|---|---|---|
| Drug-Tolerant Cells | promotes | cell_type | 0.90 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| p38α Inhibitor and PRMT1 Activator Combination to Restore Ph | 0.879 | neurodegeneration | What is the therapeutic window between i |
| Small-Molecule Modulation of G3BP1 Condensate Dynamics via P | 0.400 | neurodegeneration | How do disease-associated mutations in G |
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| MAPK pathway inhibition by QTJD through butyrate mechanism | exploratory | Mycoplasma pneumoniae pneumoni | 0.900 | 0.00 | Mouse macrophages | proposed | N/A |
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning PRMT in their description or question text
No additional research found