gene

PPP3R1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PPP3R1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

5Connections

0Hypotheses

0Analyses

5Outgoing

0Incoming

0Experiments

0Debates

Summary

Page for PPP3R1 Gene

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🧬 Gene Info

Gene Symbol	PPP3R1
Chromosome	2p15
Protein Type	Phosphatase
Function	is an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight	19 kDa
Pathways	mitogen-activated protein kinase signaling pathway
GeneCards	PPP3R1
Human Protein Atlas	PPP3R1
Associated Diseases	Alzheimer's disease
KG Connections	5 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

PPP3R1 Gene

gene · 1040 words

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Pathway Diagram

graph TD
    PPP3R1["PPP3R1"]
    TFEB["TFEB"]
    PPP3R1 -->|"activates"| TFEB
    Alzheimer_s_disease{"Alzheimer's disease"}
    PPP3R1 -->|"associated with"| Alzheimer_s_disease
    axon_guidance["axon guidance"]
    PPP3R1 -->|"participates in"| axon_guidance
    glutamatergic_synapse["glutamatergic synapse"]
    PPP3R1 -->|"participates in"| glutamatergic_synapse
    long_term_potentiation["long-term potentiation"]
    PPP3R1 -->|"participates in"| long_term_potentiation
    mitogen_activated_protein_kinase_signali(["mitogen-activated protein kinase signaling pathway"])
    PPP3R1 -->|"participates in"| mitogen_activated_protein_kinase_signali
    neurodegeneration["neurodegeneration"]
    PPP3R1 -->|"implicated in"| neurodegeneration
    style PPP3R1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (5)

Target	Relation	Type	Str
Alzheimer's disease	associated_with	disease	0.80
axon guidance	participates_in	biological_process	0.70
glutamatergic synapse	participates_in	biological_process	0.70
long-term potentiation	participates_in	biological_process	0.70
mitogen-activated protein kinase signaling pathway	participates_in	pathway	0.70

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning PPP3R1 in their description or question text

No additional research found