gene

POMGNT1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about POMGNT1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1Connections

0Hypotheses

0Analyses

0Outgoing

1Incoming

0Experiments

0Debates

Summary

Page for POMGNT1 - Protein O-Linked Mannose N-Acetylglucosaminyltransferase 1

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🧬 Gene Info

Gene Symbol	POMGNT1
Full Name	Protein O-Linked Mannose N-Acetylglucosaminyltransferase 1
Aliases	Page for POMGNT1, Page for POMGNT1 Protein
Chromosome	1p13.3
Function	is a type II membrane protein localized to the Golgi apparatus.
Primary Expression	the brain during development and in adulthood [@brain_glycosylation_2015]:
Subcellular Localization	the Golgi apparatus. It catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to O-mannose residues on
Molecular Weight	81 kDa
UniProt ID	[Q9P2F5](https://www.uniprot.org/uniprot/Q9P2F5)
Ensembl ID	ENSG00000145014
GeneCards	POMGNT1
Human Protein Atlas	POMGNT1
N-terminal cytoplasmic tail	Sorting and localization signals
Transmembrane domain	Type II membrane protein architecture
Stem region	Flexible linker
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

POMGNT1 - Protein O-Linked Mannose N-Acetylglucosaminyltransferase 1

gene · 1420 words

→

POMGNT1 Protein - Protein O-Mannose Beta-1,2-N-Acetylglucosaminyltransferase

protein · 621 words

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Pathway Diagram

graph TD
    POMGNT1["POMGNT1"]
    neurodegeneration["neurodegeneration"]
    POMGNT1 -->|"implicated_in"| neurodegeneration
    style POMGNT1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (1)

Source	Relation	Type	Str
DAG1	interacts_with	gene	0.80

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning POMGNT1 in their description or question text

No additional research found