gene

OPALIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about OPALIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Gene profile for OPALIN - a myelin-specific protein in oligodendrocytes

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🧬 Gene Info

Gene Symbol	OPALIN
Full Name	Oligodendrocyte Myelin Membrane Protein
Aliases	Gene profile for OPALIN
Chromosome	10q22.2
Function	is a membrane protein specifically and highly expressed in oligodendrocytes and the myelin sheath within the central nervous system.
Primary Expression	oligodendrocytes and the myelin sheath within the central nervous system
Molecular Weight	60 kDa
Amino Acids	30 aa
GeneCards	OPALIN
Human Protein Atlas	OPALIN
N-terminal region	Contains a signal peptide sequence that targets the protein to the secretory pathway
Extracellular domain	The majority of the protein is extracellular, with potential N-glycosylation sites
Single transmembrane domain	A hydrophobic transmembrane region anchors the protein in the membrane
C-terminal intracellular tail	A short cytoplasmic domain that may participate in signaling
Full-length isoform	The predominant form in mature oligodendrocytes
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

OPALIN — Oligodendrocyte Myelin Membrane Protein

gene · 2228 words

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Pathway Diagram

graph TD
    OPALIN["OPALIN"]
    neurodegeneration["neurodegeneration"]
    OPALIN -->|"implicated_in"| neurodegeneration
    style OPALIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning OPALIN in their description or question text

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