gene 2,228 words KG: OPALIN
Contents

OPALIN — Oligodendrocyte Myelin Membrane Protein

🧬 Gene Info
Gene SymbolOPALIN
Full NameOligodendrocyte Myelin Membrane Protein
AliasesGene profile for OPALIN
Chromosome10q22.2
Functionis a membrane protein specifically and highly expressed in oligodendrocytes and the myelin sheath within the central nervous system.
Primary Expressionoligodendrocytes and the myelin sheath within the central nervous system
Molecular Weight60 kDa
Amino Acids30 aa
GeneCardsOPALIN
Human Protein AtlasOPALIN
N-terminal regionContains a signal peptide sequence that targets the protein to the secretory pathway
Extracellular domainThe majority of the protein is extracellular, with potential N-glycosylation sites
Single transmembrane domainA hydrophobic transmembrane region anchors the protein in the membrane
C-terminal intracellular tailA short cytoplasmic domain that may participate in signaling
Full-length isoformThe predominant form in mature oligodendrocytes
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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