Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NRG1/ERBB4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| neurodegeneration | associated_with | disease | 0.40 |
| BACE1 | co_associated_with | gene | 0.30 |
| NRG1 | co_associated_with | gene | 0.30 |
| Source | Relation | Type | Str |
|---|---|---|---|
| h-73124693 | targets | hypothesis | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| BACE1/NRG1 Axis Dysfunction Drives Excitatory/Inhibitory Imb | 0.743 | neurodegeneration | What are the physiological functions of |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-15 | 1 hypotheses Top: 0.743
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Neuregulin1-ErbB4 Signaling Involved in Acupuncture Promoting Myelin Regeneratio [PMID:41801841] | Shen J, Zhao Y, Jiang C, Huang Y, Wang L | J Vis Exp | 2026 | 0 |
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning NRG1/ERBB4 in their description or question text
No additional research found