SLC11A1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolSLC11A1
Namesolute carrier family 11 member 1
Typeprotein-coding
Sourcemygene

Summary

This gene is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disea

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This is an externally resolved entity

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