protein

NMDAR2B

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NMDAR2B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

2Connections

0Hypotheses

0Analyses

2Outgoing

0Incoming

0Experiments

0Debates

Summary

NMDA Receptor Subunit NR2B (GRIN2B)

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🔬 Protein Info

Gene Symbol	NMDAR2B
Function	The NMDA receptor subunit NR2B (GRIN2B gene product) is a modulatory subunit that combines with NR1 to form functional NMDA receptors.
Subcellular Localization	Plasma membrane, postsynaptic density
Molecular Weight	166 kDa
UniProt ID	Q13224
GeneCards	NMDAR2B
Human Protein Atlas	NMDAR2B
Associated Diseases	neuropathic pain
Interactions	PKA
KG Connections	2 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: NMDAR2B — AlphaFold Q13224 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

NMDA Receptor Subunit NR2B (GRIN2B)

protein · 634 words

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Pathway Diagram

graph TD
    NMDAR2B["NMDAR2B"]
    PKA["PKA"]
    NMDAR2B -->|"activates"| PKA
    neuropathic_pain["neuropathic pain"]
    NMDAR2B ==>|"causes"| neuropathic_pain
    neurodegeneration["neurodegeneration"]
    NMDAR2B -->|"implicated in"| neurodegeneration
    style NMDAR2B fill:#1a237e,stroke:#4fc3f7,color:#4fc3f7

Outgoing (2)

Target	Relation	Type	Str
PKA	activates	protein	0.90
neuropathic pain	causes	phenotype	0.90

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning NMDAR2B in their description or question text

No additional research found