protein

NAV18PROTEIN

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about NAV18PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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🔬 Protein Info

Gene Symbol	NAV18PROTEIN
Full Name	nav18-protein
Protein Type	Protein
Function	is a voltage-gated sodium channel predominantly expressed in peripheral sensory neurons, where it plays a crucial role in pain signal transmission.
Primary Expression	peripheral sensory neurons, where it plays a crucial role in pain signal transmission
UniProt ID	Search UniProt
GeneCards	NAV18PROTEIN
Human Protein Atlas	NAV18PROTEIN
Slow inactivation kinetics	The channel remains open longer than TTX-sensitive channels
Rapid recovery from inactivation	Allows faster subsequent action potentials
Depolarized resting potential	Maintains readiness for firing
Small-diameter C-fiber nociceptors	Unmyelinated fibers that transmit dull, aching pain
Aδ-fiber nociceptors	Lightly myelinated fibers that transmit sharp, initial pain
Medium-diameter neurons	Some proprioceptive and mechanoreceptive neurons
Nociceptive neurons	Both peptidergic and non-peptidergic
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: NAV18PROTEIN — AlphaFold SEARCH Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

nav18-protein

protein · 1478 words

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Pathway Diagram

graph TD
    NAV18PROTEIN["NAV18PROTEIN"]
    neurodegeneration["neurodegeneration"]
    NAV18PROTEIN -->|"implicated_in"| neurodegeneration
    style NAV18PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

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Related Research

Hypotheses and analyses mentioning NAV18PROTEIN in their description or question text

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