| Gene Symbol | NAV18PROTEIN |
| Full Name | nav18-protein |
| Protein Type | Protein |
| Function | is a voltage-gated sodium channel predominantly expressed in peripheral sensory neurons, where it plays a crucial role in pain signal transmission. |
| Primary Expression | peripheral sensory neurons, where it plays a crucial role in pain signal transmission |
| UniProt ID | Search UniProt |
| GeneCards | NAV18PROTEIN |
| Human Protein Atlas | NAV18PROTEIN |
| Slow inactivation kinetics | The channel remains open longer than TTX-sensitive channels |
| Rapid recovery from inactivation | Allows faster subsequent action potentials |
| Depolarized resting potential | Maintains readiness for firing |
| Small-diameter C-fiber nociceptors | Unmyelinated fibers that transmit dull, aching pain |
| Aδ-fiber nociceptors | Lightly myelinated fibers that transmit sharp, initial pain |
| Medium-diameter neurons | Some proprioceptive and mechanoreceptive neurons |
| Nociceptive neurons | Both peptidergic and non-peptidergic |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!