gene

MT-ND1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MT-ND1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

11Connections
0Hypotheses
3Analyses
6Outgoing
5Incoming
0Experiments
5Debates

Summary

Page for MT-ND1 Gene - Mitochondrial NADH Dehydrogenase Subunit 1

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🧬 Gene Info
Gene SymbolMT
FunctionCytochrome b is a key component of Complex III (ubiquinol-cytochrome c reductase), which catalyzes the transfer of electrons from ubiquinol to cytochrome c.
GeneCardsMT
Human Protein AtlasMT
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Wiki Pages (1)

Knowledge base pages for this entity

MT-ND1 Gene - Mitochondrial NADH Dehydrogenase Subunit 1

gene · 526 words

Pathway Diagram

graph TD
    MT_ND1["MT-ND1"]
    oxidative_phosphorylation["oxidative phosphorylation"]
    PS_COOH["PS-COOH"]

    MT_ND1 -->|"involved in"| oxidative_phosphorylation
    PS_COOH -->|"downregulates"| MT_ND1

    style MT_ND1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#fff
    style oxidative_phosphorylation fill:#1a3a1a,stroke:#81c784,stroke-width:2px,color:#fff
    style PS_COOH fill:#1a1a2e,stroke:#888,stroke-width:2px,color:#fff

Outgoing (6)

TargetRelationTypeStr
benchmark_ot_ad_answer_key:MT-ND1data_indataset_row0.00
ds-83b31ef18d49provides_data_fordataset1.00
oxidative phosphorylationinvolved_inpathway0.90
bioenergetic failurecausesmechanism0.70
mitochondrial OXPHOSassociated_withmechanism0.70

Incoming (5)

SourceRelationTypeStr
benchmark_ot_ad_answer_key:MT-ND1data_indataset_row0.00
ds-83b31ef18d49data_indataset1.00
PS-COOHdownregulatescompound0.90
h-420db533targetshypothesis0.90
Ps-Coohdownregulatescompound0.80

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (3)

Scientific analyses that reference this entity

Proteomics Differential Expression in AD CSF and Brain Tissue

neurodegeneration | 2026-04-16 | 1 hypotheses Top: 0.865

Gene Co-expression Network Analysis of AD Progression Modules

neurodegeneration | 2026-04-16 | 1 hypotheses Top: 0.844

CRISPR-based therapeutic approaches for neurodegenerative diseases

neurodegeneration | 2026-04-03 | 14 hypotheses Top: 0.850

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found

Debates (5)

Multi-agent debates referencing this entity

What co-expression modules are shared and unique across brain regions in AD, and

closed · Rounds: 4 · Score: 0.70 · 2026-04-21

Which proteins are differentially expressed in AD CSF and brain tissue, and do t

closed · Rounds: 4 · Score: 0.70 · 2026-04-21

Is a 12-protein CSF panel superior to existing plasma p-tau217 for clinical AD p

closed · Rounds: 4 · Score: 0.70 · 2026-04-16

Is TYROBP a genuine therapeutic target in AD, or is it a downstream marker of mi

closed · Rounds: 4 · Score: 0.70 · 2026-04-16

Evaluate the potential of CRISPR/Cas9 and related gene editing technologies for

closed · Rounds: 4 · Score: 0.95 · 2026-04-03

Related Research

Hypotheses and analyses mentioning MT-ND1 in their description or question text

No additional research found