gene

MT-CO1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MT-CO1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

3Connections
0Hypotheses
2Analyses
2Outgoing
1Incoming
0Experiments
4Debates

Summary

Page for MT-CO1 Gene - Mitochondrially Encoded Cytochrome C Oxidase I

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🧬 Gene Info
Gene SymbolMT
FunctionCytochrome b is a key component of Complex III (ubiquinol-cytochrome c reductase), which catalyzes the transfer of electrons from ubiquinol to cytochrome c.
GeneCardsMT
Human Protein AtlasMT
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Wiki Pages (2)

Knowledge base pages for this entity

MT-CO1 Protein (Cytochrome c Oxidase I)

protein · 671 words

MT-CO1 Gene - Mitochondrially Encoded Cytochrome C Oxidase I

gene · 548 words

Pathway Diagram

graph TD
    A["Regulatory elements"] --> B["MT CO1 gene"]
    B --> C["mRNA transcript"]
    C --> D["Protein product"]
    D --> E["Cellular function"]
    E --> F["Disease relevance"]
    B --> G["Variant effects"]
    G --> F
    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    class B gene
    class D protein

Outgoing (2)

TargetRelationTypeStr
mitochondrial OXPHOSassociated_withmechanism0.70
Aβ accumulationprecedesmechanism0.70

Incoming (1)

SourceRelationTypeStr
h-28d5b559targets_genehypothesis0.90

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (2)

Scientific analyses that reference this entity

Gene Co-expression Network Analysis of AD Progression Modules

neurodegeneration | 2026-04-16 | 1 hypotheses Top: 0.844

Spatial Transcriptomics Analysis of Alzheimer's Disease Brain Regions

neurodegeneration | 2026-04-16 | 2 hypotheses

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found

Debates (4)

Multi-agent debates referencing this entity

How does spatial gene expression in the hippocampus and entorhinal cortex distin

closed · Rounds: 4 · Score: 0.70 · 2026-04-21

What co-expression modules are shared and unique across brain regions in AD, and

closed · Rounds: 4 · Score: 0.70 · 2026-04-21

Is TYROBP a genuine therapeutic target in AD, or is it a downstream marker of mi

closed · Rounds: 4 · Score: 0.70 · 2026-04-16

Do spatial transcriptomic neighborhoods provide sufficient discriminative power

closed · Rounds: 4 · Score: 0.70 · 2026-04-16

Related Research

Hypotheses and analyses mentioning MT-CO1 in their description or question text

No additional research found