MMP2

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolMMP2
Namematrix metallopeptidase 2
Typeprotein-coding
Sourcemygene

Summary

This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the ce

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