concept

LANCL1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about LANCL1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

20Connections

0Hypotheses

0Analyses

12Outgoing

8Incoming

0Experiments

0Debates

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💡 Concept Info

Name	LANCL1
Key Genes/Proteins	ALS, AMYOTROPHIC LATERAL SCLEROSIS, AND, MOTOR NEURONS, NEURODEGENERATION, NEURON
Related Diseases	Als, Amyotrophic Lateral Sclerosis, Neurodegeneration
Related Pathways	Sod1

Pathway Diagram

graph TD
    LANCL1["LANCL1"]
    LANCL1 -->|"activates"| Amyotrophic_Lateral_Sclerosis["Amyotrophic Lateral Sclerosis"]
    LANCL1 -->|"activates"| Als["Als"]
    LANCL1 -->|"causes"| Neurodegeneration["Neurodegeneration"]
    LANCL1 -.protects against.-> motor_neuron_survival["motor neuron survival"]
    LANCL1 -->|"regulates"| antioxidant_defense["antioxidant defense"]
    LANCL1 -->|"activates"| Neuron["Neuron"]
    LANCL1 -->|"activates"| NEURON["NEURON"]
    LANCL1 -->|"activates"| ALS["ALS"]
    SOD1["SOD1"] -->|"activates"| LANCL1
    NEURON -->|"activates"| LANCL1
    ALS -->|"activates"| LANCL1
    NEURODEGENERATION["NEURODEGENERATION"] -->|"causes"| LANCL1
    AMYOTROPHIC_LATERAL_SCLEROSIS["AMYOTROPHIC LATERAL SCLEROSIS"] -->|"activates"| LANCL1
    MOTOR_NEURONS["MOTOR NEURONS"] -->|"activates"| LANCL1
    AND["AND"] -->|"activates"| LANCL1

Outgoing (12)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:LANCL1	data_in	dataset_row	0.00
Amyotrophic Lateral Sclerosis	activates	disease	0.65
Als	activates	disease	0.65
Neurodegeneration	causes	disease	0.65
Neuron	activates	cell_type	0.60
motor neuron survival	protects_against	phenotype	0.60
antioxidant defense	regulates	pathway	0.60
NEURON	activates	gene	0.60
ALS	activates	gene	0.60
Sod1	activates	pathway	0.60
SOD1	activates	gene	0.60
Neuron	expressed_in	cell_type	0.55

Incoming (8)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:LANCL1	data_in	dataset_row	0.00
SOD1	activates	gene	0.60
NEURON	activates	gene	0.60
ALS	activates	gene	0.60
NEURODEGENERATION	causes	gene	0.60
AMYOTROPHIC LATERAL SCLEROSIS	activates	gene	0.60
MOTOR NEURONS	activates	gene	0.60
AND	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning LANCL1 in their description or question text

No additional research found