HTRA2

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolHTRA2
NameHtrA serine peptidase 2
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splic

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