concept

GD3 SYNTHASE

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GD3 SYNTHASE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

15Connections

0Hypotheses

0Analyses

11Outgoing

4Incoming

0Experiments

0Debates

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💡 Concept Info

Name	GD3 SYNTHASE
Key Genes/Proteins	AMYLOID-BETA

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

GD3 Synthase (ST8SIA1)

enzyme · 637 words

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Pathway Diagram

graph TD
    GD3_SYNTHASE["GD3 SYNTHASE"]
    GD3_SYNTHASE -->|"catalyzes"| Gd3["Gd3"]
    GD3_SYNTHASE -->|"catalyzes"| Ganglioside_Biosynthesis["Ganglioside Biosynthesis"]
    GD3_SYNTHASE -.protects against.-> Parkinsonism["Parkinsonism"]
    GD3_SYNTHASE -.protects against.-> Executive_Dysfunction["Executive Dysfunction"]
    GD3_SYNTHASE -->|"regulates"| Gm1["Gm1"]
    GD3_SYNTHASE -->|"regulates"| Gangliosides["Gangliosides"]
    GD3_SYNTHASE -->|"mediates"| Neuroprotection["Neuroprotection"]
    GD3_SYNTHASE -->|"reduces"| amyloid_beta_plaque["amyloid-beta plaque"]
    ST8SIA1["ST8SIA1"] -->|"encodes"| GD3_SYNTHASE
    ASTROCYTE["ASTROCYTE"] -->|"interacts"| GD3_SYNTHASE

Outgoing (11)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:GD3 SYNTHASE	data_in	dataset_row	0.00
Executive Dysfunction	protects_against	phenotype	0.95
Parkinsonism	protects_against	disease	0.95
Neuroprotection	mediates	process	0.90
Gangliosides	regulates	compound	0.90
amyloid-beta plaque	reduces	process	0.90
Brain Gangliosides	modulates	compound	0.85
MEMORY	improves	process	0.80
ABETA	interacts_with	protein	0.80
AMYLOID-BETA	regulates	protein	0.80
MPTP-induced Parkinsonism	protects_against	disease	0.80

Incoming (4)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:GD3 SYNTHASE	data_in	dataset_row	0.00
ST8SIA1	associated_with	gene	0.95
ST8SIA1	expressed_in	gene	0.90
ASTROCYTE	interacts_with	cell_type	0.70

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning GD3 SYNTHASE in their description or question text

No additional research found