gene

GBAP1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GBAP1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

7Connections

0Hypotheses

0Analyses

5Outgoing

2Incoming

0Experiments

0Debates

Summary

Page for GBAP1

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🧬 Gene Info

Gene Symbol	GBAP1
Full Name	Glucosylceramidase Beta Pseudogene 1
Chromosome	1q21.3
Function	is a pseudogene located on chromosome 1q21, adjacent to the functional GBA gene.
Pathways	Sphingolipid
UniProt ID	[Q9HCG7](https://www.uniprot.org/uniprot/Q9HCG7)
NCBI Gene ID	26235
Ensembl ID	ENSG00000144040
GeneCards	GBAP1
Human Protein Atlas	GBAP1
Genomic coordinates	chr1:155,234,654-155,245,892 (GRCh38)
Orientation	Forward strand
Size	~11 kb
Distance from GBA	~16 kb downstream
Highest expression	Brain tissue (cerebral cortex, cerebellum)
Associated Diseases	neurodegeneration
Interactions	GBA
KG Connections	7 knowledge graph edges
Databases	GeneCards HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

GBAP1

gene · 1377 words

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Pathway Diagram

graph TD
    GBAP1["GBAP1"]
    Ms["Ms"]
    GBA["GBA"]
    Sphingolipid["Sphingolipid"]
    neurodegeneration["neurodegeneration"]

    GBAP1 -->|"regulates"| Ms
    GBAP1 -->|"activates"| GBA
    GBAP1 -->|"regulates"| Sphingolipid
    GBAP1 -->|"implicated in"| neurodegeneration

    style GBAP1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#fff
    style Ms fill:#3e1a1a,stroke:#ef5350,stroke-width:2px,color:#fff
    style GBA fill:#1a237e,stroke:#ce93d8,stroke-width:2px,color:#fff
    style Sphingolipid fill:#1a3a1a,stroke:#81c784,stroke-width:2px,color:#fff
    style neurodegeneration fill:#1a1a2e,stroke:#888,stroke-width:2px,color:#fff

Outgoing (5)

Target	Relation	Type	Str
Ms	regulates	disease	0.65
RNA	associated_with	gene	0.60
RNA	expressed_in	gene	0.60
Sphingolipid	regulates	pathway	0.60
GBA	activates	gene	0.60

Incoming (2)

Source	Relation	Type	Str
GBA1	associated_with	gene	0.60
GBA1	expressed_in	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning GBAP1 in their description or question text

No additional research found