FZD7

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolFZD7
Namefrizzled class receptor 7
Typeprotein-coding
Sourcemygene

Summary

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differe

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