gene

EPHA6

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about EPHA6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Ephrin Type-A Receptor 6, a receptor tyrosine kinase involved in neuronal development, synaptic plasticity, and implicated in Alzheimer's disease and other neurodegenerative disorders

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🧬 Gene Info

Gene Symbol	EPHA6
Full Name	Ephrin Type-A Receptor 6
Chromosome	3q21.1
Protein Type	Receptor
Function	is a member of the Eph family of receptor tyrosine kinases that play critical roles in development and plasticity of the central nervous system[@kawasaki2006].
Primary Expression	Cortex, hippocampus, cerebellum, basal ganglia
Molecular Weight	110 kDa
Amino Acids	550 aa
Exons	17
UniProt ID	Q9Y232
NCBI Gene ID	28534
Ensembl ID	ENSG00000048028
GeneCards	EPHA6
Human Protein Atlas	EPHA6
Associated Diseases	Alzheimer's Disease, Parkinson's Disease
Databases	GeneCards HPA STRING

🔮 Predicted Structure: EPHA6 — AlphaFold Q9Y232 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

EPHA6 — Ephrin Type-A Receptor 6

gene · 3363 words

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Pathway Diagram

graph TD
    EPHA6["EPHA6"]
    neurodegeneration["neurodegeneration"]
    EPHA6 -->|"implicated_in"| neurodegeneration
    style EPHA6 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning EPHA6 in their description or question text

No additional research found