Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Dendritic spine density: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| Cognitive Function | promotes | phenotype | 0.85 |
| spatial learning and memory | contributes_to | phenotype | 0.82 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Tong-Qiao-Huo-Xue Decoction | associated_with | drug | 0.92 |
| 18568035 | reduce | paper | 0.90 |
| Aerobic Exercise | upregulates | process | 0.90 |
| TDP-43 | increases | protein | 0.90 |
| VEGF/ERK signaling pathway | upregulates | pathway | 0.88 |
| MTOR | regulates | protein | 0.85 |
| mTOR Signaling | upregulates | pathway | 0.85 |
| Chronic Restraint Stress | downregulates | process | 0.80 |
| BDNF | activates | protein | 0.70 |
| Synaptic protein synthesis | preserves | process | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-26 | 7 hypotheses Top: 0.605
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning Dendritic spine density in their description or question text
No additional research found