Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about DYSTROPHIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | DYSTROPHIN |
| Function | Dystrophin is a large cytoskeletal protein critical for muscle fiber stability and function. |
| Molecular Weight | 427 kDa |
| GeneCards | DYSTROPHIN |
| Human Protein Atlas | DYSTROPHIN |
| Associated Diseases | disease |
| Interactions | GAD1, MAP |
| KG Connections | 5 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
flowchart TD
DYSTROPHIN(["DYSTROPHIN"])
GAD1(["GAD1"])
disease["disease"]
MOTOR_NEURONS("MOTOR NEURONS")
NEURONS("NEURONS")
MAP(["MAP"])
DYSTROPHIN -.->|"inhibits"| GAD1
DYSTROPHIN -->|"causes"| disease
DYSTROPHIN -->|"expressed in"| MOTOR_NEURONS
DYSTROPHIN -->|"expressed in"| NEURONS
MAP -.->|"inhibits"| DYSTROPHIN
style DYSTROPHIN fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff| Target | Relation | Type | Str |
|---|---|---|---|
| Dystrophinopathy | biomarker_for | disease | 0.90 |
| GAD1 | inhibits | gene | 0.50 |
| disease | causes | disease | 0.50 |
| MOTOR NEURONS | expressed_in | concept | 0.50 |
| NEURONS | expressed_in | concept | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| MAP | inhibits | protein | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning DYSTROPHIN in their description or question text
No additional research found