gene

DYNLRB1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DYNLRB1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

2Connections

0Hypotheses

0Analyses

2Outgoing

0Incoming

0Experiments

0Debates

Summary

DYNLRB1 Gene

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🧬 Gene Info

Gene Symbol	DYNLRB1
Full Name	Dynein Light Chain Roadblock Type 1
Chromosome	12q24.31
Function	DYNLRB1 is a dynein light chain that contributes to the dynein complex.
Primary Expression	neurons, especially in hippocampus
UniProt ID	[Q9NPJ3](https://www.uniprot.org/uniprotkb/Q9NPJ3/entry)
GeneCards	DYNLRB1
Human Protein Atlas	DYNLRB1
Associated Diseases	Neurodevelopmental disorders (potential)
KG Connections	2 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

DYNLRB1 Gene

gene · 666 words

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Pathway Diagram

graph TD
    DYNLRB1["DYNLRB1"]
    style DYNLRB1 fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff
    alpha_synuclein_induced_toxicity(["alpha-synuclein induced toxicity"])
    TGF_beta_signaling(("TGF-beta signaling"))
    neurodegeneration["neurodegeneration"]

    DYNLRB1 -->|"protects_against"| alpha_synuclein_induced_toxicity
    DYNLRB1 -->|"component_of"| TGF_beta_signaling
    DYNLRB1 -->|"implicated_in"| neurodegeneration

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef drug fill:#1a2a2a,stroke:#80cbc4,color:#e0e0e0
    class alpha_synuclein_induced_toxicity protein
    class TGF_beta_signaling pathway
    class neurodegeneration disease

Outgoing (2)

Target	Relation	Type	Str
alpha-synuclein induced toxicity	protects_against	process	0.85
TGF-beta signaling	component_of	pathway	0.80

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning DYNLRB1 in their description or question text

No additional research found