concept

DHRS4

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DHRS4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

13Connections

0Hypotheses

0Analyses

8Outgoing

5Incoming

0Experiments

0Debates

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💡 Concept Info

Name	DHRS4
Key Genes/Proteins	ALS, AMYOTROPHIC LATERAL SCLEROSIS, IMMUNE INFILTRATION, NEURODEGENERATION, SOD1
Related Diseases	Als, Amyotrophic Lateral Sclerosis, Neurodegeneration
Related Pathways	Sod1

Pathway Diagram

graph TD
    DHRS4[DHRS4]
    DHRS4 -->|expressed in| Als[Als]
    DHRS4 -->|expressed in| ALS[ALS]
    DHRS4 -->|expressed in| IMMUNE_INFILTRATION[IMMUNE INFILTRATION]
    DHRS4 -->|activates| Sod1[Sod1]
    DHRS4 -->|expressed in| Spinal_Cord[Spinal Cord]
    DHRS4 -->|data_in| benchmark_ot_ad_answer_key_DHR[benchmark_ot_ad_answer_key:DHRS4]
    SOD1[SOD1] -->|activates| DHRS4
    ALS -->|expressed in| DHRS4
    benchmark_ot_ad_answer_key_DHR -->|data_in| DHRS4

Outgoing (8)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:DHRS4	data_in	dataset_row	0.00
Amyotrophic Lateral Sclerosis	associated_with	disease	0.70
Als	expressed_in	disease	0.65
Neurodegeneration	associated_with	disease	0.65
ALS	expressed_in	gene	0.60
IMMUNE INFILTRATION	expressed_in	gene	0.60
Sod1	activates	pathway	0.60
Spinal Cord	expressed_in	brain_region	0.55

Incoming (5)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:DHRS4	data_in	dataset_row	0.00
NEURODEGENERATION	associated_with	gene	0.60
AMYOTROPHIC LATERAL SCLEROSIS	associated_with	gene	0.60
ALS	expressed_in	gene	0.60
SOD1	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning DHRS4 in their description or question text

No additional research found