Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CRP: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Macrophage Infiltration | contributes_to | process | 0.85 |
| Sepsis | biomarker_for | disease | 0.85 |
| Recurrent Stroke | biomarker_for | disease | 0.85 |
| cardiovascular risk | biomarker_for | disease | 0.80 |
| Liver Cirrhosis | risk_factor_for | disease | 0.75 |
| Septic Shock | biomarker_for | disease | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Selective C1q-CRP vs. C1q-IgG Axis Inhibition | 0.599 | neuroinflammation | How does Alectinib, a kinase inhibitor, |
| Circulating hs-CRP as Disease-Modifying Target via Microglia | 0.540 | immunomics | Systemic immune profiling in neurodegene |
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Binding and complement activation by C-reactive protein via the collagen-like re [PMID:2005402] | ["Jiang HX", "Siegel JN", "Gewurz H"] | J Immunol | 1991 | 0 |
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning CRP in their description or question text
No additional research found