Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CPSF6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | CPSF6 |
| Full Name | Cleavage and Polyadenylation Specific Factor 6 |
| Function | CPSF6 encodes a component of the cleavage and polyadenylation specificity factor (CPSF) complex, which is essential for mRNA 3'-end processing. |
| UniProt ID | CPSF6 |
| Ensembl ID | ENSG00000149596 |
| GeneCards | CPSF6 |
| Human Protein Atlas | CPSF6 |
| mRNA processing | Component of the CFII complex for 3'-end cleavage and polyadenylation |
| RNA splicing | Regulates alternative splicing of specific transcripts |
| Stress response | Localizes to stress granules under cellular stress |
| Chromatin regulation | Associates with chromatin in neuronal nuclei |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
CPSF6["CPSF6"]
neurodegeneration["neurodegeneration"]
CPSF6 -->|"implicated_in"| neurodegeneration
style CPSF6 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning CPSF6 in their description or question text
No additional research found