Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about COMPLEXIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | COMPLEXIN |
| Protein Family | Complexin family |
| Function | Synaptic vesicle fusion regulation |
| Primary Expression | excitatory neurons, essential for fast synchronous neurotransmitter release - CPLX2: Expressed in both excitatory and inhibit |
| Molecular Weight | 17 kDa |
| UniProt ID | Q9R0E5 (CPLX1), Q96A56 (CPLX2), Q8WV92 (CPLX3), Q7Z594 (CPLX4) |
| GeneCards | COMPLEXIN |
| Human Protein Atlas | COMPLEXIN |
| N-terminal domain | Involved in SNARE complex binding |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
COMPLEXIN["COMPLEXIN"]
neurodegeneration["neurodegeneration"]
COMPLEXIN -->|"implicated_in"| neurodegeneration
style COMPLEXIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning COMPLEXIN in their description or question text
No additional research found