protein

CHD5

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CHD5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for CHD5 Protein

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🔬 Protein Info

Gene Symbol	CHD5
Full Name	Chromodomain Helicase DNA Binding Protein 5
Chromosome	1p36.31
Function	CHD5 encodes a neuron-specific ATP-dependent chromatin remodeler.
Molecular Weight	260 kDa
UniProt ID	Q8TDC0
NCBI Gene ID	84159
Ensembl ID	ENSG00000132016
OMIM	610569
GeneCards	CHD5
Human Protein Atlas	CHD5
Transcriptional activation	CHD5 activates neuronal gene expression programs
Chromatin opening	Facilitates DNA accessibility for transcription factors
Histone modification	Associates with H3K4 methyltransferases for active marks
Neuronal differentiation	Essential for neural progenitor differentiation
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: CHD5 — AlphaFold Q8TDC0 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (4)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    CHD5["CHD5"]
    neurodegeneration["neurodegeneration"]
    CHD5 -->|"implicated_in"| neurodegeneration
    style CHD5 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning CHD5 in their description or question text

No additional research found