gene

CACNB1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CACNB1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Analyses

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Summary

Page for CACNB1 - Calcium Channel Beta-1 Subunit

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🧬 Gene Info

Gene Symbol	CACNB1
Full Name	Calcium Voltage-Gated Channel Beta Subunit 1
Aliases	Page for CACNB1, Page for CACNB1 Protein
Chromosome	17q22
Function	is an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight	65 kDa
Amino Acids	597 aa
UniProt ID	CACNB1
Ensembl ID	ENSG00000165995
GeneCards	CACNB1
Human Protein Atlas	CACNB1
Channel Trafficking	Facilitates proper localization of calcium channel complexes to the plasma membrane
Gating Modulation	Alters voltage-dependent activation and inactivation kinetics
Current Density	Increases the number of functional channels at the cell surface
Binding Partners	Interacts with the alpha-1 subunit via a high-affinity interaction domain
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: CACNB1 — AlphaFold CACNB1 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

CACNB1 - Calcium Channel Beta-1 Subunit

gene · 538 words

→

CACNB1 Protein - Calcium Channel Beta-1 Subunit

protein · 522 words

→

Pathway Diagram

graph TD
    CACNB1["CACNB1"]
    neurodegeneration["neurodegeneration"]
    CACNB1 -->|"implicated_in"| neurodegeneration
    style CACNB1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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No outgoing edges

Incoming (0)

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No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CACNB1 in their description or question text

No additional research found