protein 522 words KG: CACNB1PROTEIN
Contents

CACNB1 Protein - Calcium Channel Beta-1 Subunit

🔬 Protein Info
Gene SymbolCACNB1
Full NameCalcium Voltage-Gated Channel Beta Subunit 1
AliasesPage for CACNB1, Page for CACNB1 Protein
Chromosome17q22
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight65 kDa
Amino Acids597 aa
UniProt IDCACNB1
Ensembl IDENSG00000165995
GeneCardsCACNB1
Human Protein AtlasCACNB1
SH3 Domain (Src Homology 3)N-terminal domain involved in protein-protein interactions
SH2 Domain (Src Homology 2)Mediates binding to phosphorylated tyrosine residues
GK Domain (Guanylate Kinase)Central domain with binding activity
AID (Alpha-Interacting Domain)Critical for binding to the alpha-1 subunit of VGCCs
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

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UniProtWikipedia

Related Hypotheses (8)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Lysosomal Calcium Channel Modulation Therapy
Score: 0.70
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.67
Mitochondrial Calcium Buffering Enhancement via MCU Modulati
Score: 0.65
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (10)

Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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