entity

A53T

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about A53T: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

2Connections
0Hypotheses
1Analyses
2Outgoing
0Incoming
0Experiments
1Debates

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Wiki Pages (3)

Knowledge base pages for this entity

Canonical Page

A53T Alpha-Synuclein Transgenic Mouse Model of Parkinson's Disease

model · 556 words

SNCA A53T

disease · 3026 words

SNCA-A53T Alpha-Synuclein Neurons

cell · 2650 words

Outgoing (2)

TargetRelationTypeStr
PARKINSONS_DISEASEcausesdisease0.72
ACLYactivatesprotein0.72

Incoming (0)

SourceRelationTypeStr
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (1)

Scientific analyses that reference this entity

How does engineered C. butyricum cross the blood-brain barrier to directly bind

neurodegeneration | 2026-04-15 | 2 hypotheses Top: 0.699

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found

Debates (1)

Multi-agent debates referencing this entity

The abstract claims C. butyricum-GLP-1 crosses the BBB and binds to GLP-1 recept

closed · Rounds: 4 · Score: 0.95 · 2026-04-15