Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about 41787076: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| ent-gene-28e2cb01 | regulates | gene | 0.90 |
| microglial function | regulates | process | 0.90 |
| ent-gene-28e2cb01 | is implicated in | gene | 0.90 |
| Alzheimer's disease pathogenesis | is implicated in | mechanism | 0.90 |
| ent-gene-28e2cb01 | implicated in | gene | 0.90 |
| ent-drug-4d620535 | demonstrated sustained target engagement and pharmacodynamic responses in | drug | 0.90 |
| Soluble TREM2 | caused reductions in | biomarker | 0.90 |
| ent-drug-4d620535 | did not meet primary endpoint of change from baseline in | drug | 0.90 |
| ent-drug-4d620535 | demonstrated sustained target engagement in | drug | 0.90 |
| central nervous system | demonstrated sustained target engagement in | organ | 0.90 |
| ent-drug-4d620535 | reduced | drug | 0.90 |
| ent-drug-4d620535 | increased | drug | 0.90 |
| ent-drug-4d620535 | demonstrates | drug | 0.90 |
| ent-drug-4d620535 | reduces | drug | 0.90 |
| ent-drug-4d620535 | increases | drug | 0.90 |
| ent-drug-4d620535 | associated with | drug | 0.90 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning 41787076 in their description or question text
No additional research found