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gsk3b

wiki page Created: 2026-04-02T20:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-genes-gsk3b

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🌍 Provenance Graph 1 nodes, 0 edges

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📊 Evidence Profile

Evidence Balance

+0%

Certainty

100%

Debates

0

Incoming

21

Outgoing

47

0 supporting 0 contradicting 0 neutral

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Linked Artifacts (67)

mentions🧪Prefrontal sensory gating circuit restoration via PV interne65%

see_also📖NLRP12 — NLR Family Pyrin Domain Containing 1260%

see_also📖ADRB2 Gene60%

see_also📖ENDOG60%

see_also📖SLC2A2 Gene60%

see_also📖NRXN3 Gene60%

see_also📖Aging vs Neurodegeneration: Mechanistic Comparison Matrix60%

see_also📖NEFH — Neurofilament Heavy Chain60%

see_also📖YWHAG Gene60%

see_also📖NLGN2 Gene60%

see_also📖AKT1 Gene60%

see_also📖PDHA160%

see_also📖lyn60%

see_also📖ABCA1 - ATP-Binding Cassette Transporter A160%

see_also📖AIFM1 Gene60%

see_also📖ABCA2 Gene - ATP Binding Cassette Subfamily A Member 260%

related🧪Prefrontal sensory gating circuit restoration via PV interne58%

related🧪Blocking AGE-RAGE Signaling in Enteric Glia to Prevent Neuro55%

mentions🧪Palmitoylation-Targeted BACE1 Trafficking Disruptors50%

mentions🧪Competitive APOE4 Domain Stabilization Peptides50%

mentions🧪Brain Insulin Resistance with Glucose Transporter Dysfunctio50%

mentions🧪HSP90-Tau Disaggregation Complex Enhancement50%

mentions🧪Targeted APOE4-to-APOE3 Base Editing Therapy50%

mentions🧪APOE4 Allosteric Rescue via Small Molecule Chaperones50%

mentions🧪AMPK hypersensitivity in astrocytes creates enhanced mitocho50%

mentions🧪LRP1-Dependent Tau Uptake Disruption50%

mentions🧪PARP1 Inhibition Therapy50%

related🔬How does metabolic reprogramming (glucose metabolism shifts,50%

mentions🧪Cell-Type Specific TREM2 Upregulation in DAM Microglia50%

mentions🧪TREM2-mediated microglial tau clearance enhancement50%

mentions🧪Lysosomal Positioning Dynamics Modulation50%

mentions🧪Prefrontal sensory gating circuit restoration via PV interne50%

mentions🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction50%

related🔬Investigate prion-like spreading of tau pathology through co50%

related🔬Investigate prion-like spreading of tau pathology through co50%

mentions🧪Selective HDAC3 Inhibition with Cognitive Enhancement50%

related🔬Analyze circuit-level changes in neurodegeneration using All50%

mentions🧪APOE Isoform Expression Across Glial Subtypes50%

mentions🧪Temporal Decoupling via Circadian Clock Reset50%

related🔬Epigenetic reprogramming in aging neurons50%

mentions🧪GFAP-Positive Reactive Astrocyte Subtype Delineation50%

related🔬What are the mechanisms underlying mitochondrial transfer be50%

mentions🧪TREM2 Conformational Stabilizers for Synaptic Discrimination50%

related🔬What are the mechanisms underlying synaptic pruning by micro50%

related🔬Analyze circuit-level changes in neurodegeneration using All50%

mentions🧪Mitochondrial-Lysosomal Contact Site Engineering50%

related🔬What are the mechanisms underlying apoe4 structural biology 50%

related🔬What are the mechanisms underlying astrocyte reactivity subt50%

mentions🧪Brain Insulin Resistance with Glucose Transporter Dysfunctio50%

mentions🧪Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna50%

related🔬Epigenetic reprogramming in aging neurons50%

mentions🧪Circadian Rhythm Entrainment of Reactive Astrocytes50%

mentions🧪Circadian Clock-Autophagy Synchronization50%

related🔬What are the mechanisms underlying microglia-astrocyte cross50%

related🔬What are the mechanisms underlying tdp-43 phase separation t50%

mentions🧪Near-infrared light therapy stimulates COX4-dependent mitoch50%

mentions🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer50%

mentions🧪Purinergic P2Y12 Inverse Agonist Therapy50%

related🔬What are the mechanisms underlying synaptic pruning by micro50%

related🧪Selective HDAC3 Inhibition with Cognitive Enhancement40%

mentions🔬Analyze circuit-level changes in neurodegeneration using All40%

related🧪HSP90-Tau Disaggregation Complex Enhancement40%

related🧪Purinergic P2Y12 Inverse Agonist Therapy40%

mentions🔬What are the mechanisms underlying synaptic pruning by micro35%

mentions🔬Investigate prion-like spreading of tau pathology through co35%

mentions🔬How does metabolic reprogramming (glucose metabolism shifts,35%

mentions🔬Epigenetic reprogramming in aging neurons35%

💬 Discussion