📖

entities-gba

wiki page Created: 2026-04-02T17:01:41 By: crosslink-v2 Quality: 50% ✓ SciDEX ID: wiki-entities-gba
🌍 Provenance Graph 1 nodes, 0 edges

No provenance edges found

📊 Evidence Profile
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
61
Outgoing
46
0 supporting 0 contradicting 0 neutral
View full evidence profile →
Linked Artifacts (106)
mentions🧫Validate Mitochondria-Lysosome Contact Site Dysfunction in P90%
mentions🔬Analysis question not specified75%
mentions🔬How to break the GBA-alpha-synuclein bidirectional loop for 75%
related🧫Cytochrome Therapeutics70%
mentions🧫Alpha-Synuclein Aggregation Triggers — Sporadic PD Initiatio70%
mentions🧫Prodromal Parkinson's Disease Biomarker Development — E70%
related🧫Cytochrome Therapeutics70%
related🧫Validate Mitochondria-Lysosome Contact Site Dysfunction in P70%
mentions🧫DLB Treatment Response Biomarkers — Predicting Cholinesteras70%
mentions🧫Validate Mitochondria-Lysosome Contact Site Dysfunction in P70%
mentions🧫DNA Damage Repair Deficiency Validation Study in Parkinson&#70%
mentions🧫Genetic Risk Modifiers in DLB Phenotype70%
mentions🧫LRRK2/GBA Mutation Carrier Resilience — Why Some Carriers Ne70%
mentions🧫GLP-1 Agonist Responder Prediction Study — Precision Medicin70%
mentions🧫Experiment: Multi-Ethnic PD GWAS70%
mentions🧫MLCS Quantification in Parkinson's Disease70%
mentions🧫Autophagy Enhancement Drug Screening for Neurodegeneration70%
mentions🧫Synaptic Vesicle Trafficking Dysfunction Validation in Parki70%
related🔬Analysis question not specified67%
related🔬How to break the GBA-alpha-synuclein bidirectional loop for 67%
related🧫Synaptic Vesicle Trafficking Dysfunction Validation in Parki63%
related🧫GLP-1 Agonist Responder Prediction Study — Precision Medicin63%
related🧫MLCS Quantification in Parkinson's Disease63%
related🧫Experiment: Multi-Ethnic PD GWAS63%
related🧫LRRK2/GBA Mutation Carrier Resilience — Why Some Carriers Ne63%
related🧫DNA Damage Repair Deficiency Validation Study in Parkinson&#63%
related🧫Alpha-Synuclein Aggregation Triggers — Sporadic PD Initiatio63%
related🧫Validate Mitochondria-Lysosome Contact Site Dysfunction in P63%
related🧫Autophagy Enhancement Drug Screening for Neurodegeneration63%
related🧫Prodromal Parkinson's Disease Biomarker Development — E63%
related🧫Genetic Risk Modifiers in DLB Phenotype63%
related🧫DLB Treatment Response Biomarkers — Predicting Cholinesteras63%
see_also📖Aging vs Neurodegeneration: Mechanistic Comparison Matrix60%
see_also📖VPS11 — Vacuolar Protein Sorting 1160%
see_also📖HEXA Gene - Hexosaminidase Alpha60%
see_also📖DDX1 Gene60%
see_also📖TMEM175 Protein60%
see_also📖TMEM175 Lysosomal Modulation Therapy60%
see_also📖WIPI1 Gene60%
see_also📖scn2a60%
see_also📖RAB29 — RAS-Related Protein Rab-2960%
see_also📖ddc60%
see_also📖RALB Gene - RAS-Related Protein Ral-B60%
see_also📖Accelerating Medicines Partnership for Alzheimer's Dise60%
see_also📖HEXA (Redirect)60%
see_also📖proteins-vps13d-protein60%
see_also📖Lysosomal Dysfunction in Progressive Supranuclear Palsy60%
see_also📖ABCD3 Gene60%
see_also📖DOCK2 Gene60%
see_also📖ABCA7 (Redirect)60%
see_also📖Nuclear Receptor Related 1 (NURR1)60%
see_also📖VPS13D Gene60%
see_also📖NRXN1 Gene60%
see_also📖GNB4 Gene — G Protein Subunit Beta 460%
see_also📖WDFY3 Gene60%
see_also📖CELF4 — CUGBP Elav-Like Family Member 460%
see_also📖Autophagy-Lysosomal Pathway60%
see_also📖DCTN2 Protein - Dynactin Subunit 260%
see_also📖GBAP160%
see_also📖VPS13D Protein60%
see_also📖NURR1 Gene60%
see_also📖SCN8A Gene - Nav1.660%
see_also📖HEXB Gene - Hexosaminidase Beta60%
see_also📖SCN4A Gene60%
see_also📖GNAI3 — G Protein Subunit Alpha I360%
see_also📖TMEM175 Protein60%
see_also📖PSMB960%
see_also📖OGDH — Oxoglutarate Dehydrogenase60%
see_also📖bsn60%
see_also📖Lysosomal Dysfunction in Neurodegeneration60%
see_also📖TMEM175 Gene60%
see_also📖SLC17A5 Gene60%
see_also📖AKT1 Gene60%
see_also📖pik3cb60%
see_also📖LIPA Gene60%
see_also📖WIPI1 Protein60%
see_also📖adam1060%
see_also📖Actin Cytoskeleton Dynamics in Neurodegeneration60%
see_also📖SCARB2 Gene60%
see_also📖SUMF1 Gene60%
see_also📖gnptab60%
see_also📖ACTB Gene60%
see_also📖DCTN2 - Dynactin Subunit 260%
see_also📖PILRB Gene60%
mentions🧪Lysosomal Positioning Dynamics Modulation50%
mentions🧪Mitochondrial Transfer Pathway Enhancement50%
mentions🧪APOE Isoform Expression Across Glial Subtypes50%
mentions🧪Phase-Separated Organelle Targeting50%
mentions🧪APOE4 Allosteric Rescue via Small Molecule Chaperones50%
related🔬What are the mechanisms underlying tdp-43 phase separation t50%
mentions🧪Targeted APOE4-to-APOE3 Base Editing Therapy50%
mentions🧪Cell-Type Specific TREM2 Upregulation in DAM Microglia50%
mentions🧪Competitive APOE4 Domain Stabilization Peptides50%
mentions🧪TREM2-mediated microglial tau clearance enhancement50%
mentions🧪GFAP-Positive Reactive Astrocyte Subtype Delineation50%
mentions🧪Metabolic Circuit Breaker via Lipid Droplet Modulation50%
mentions🧪Selective Acid Sphingomyelinase Modulation Therapy50%
mentions🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction50%
mentions🧪Palmitoylation-Targeted BACE1 Trafficking Disruptors50%
mentions🧪RNA Granule Nucleation Site Modulation50%
related🔬What are the mechanisms underlying astrocyte reactivity subt50%
related🔬Investigate how lipid raft composition (cholesterol metaboli50%
mentions🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer50%
mentions🧪Stress Granule Phase Separation Modulators50%
mentions🧪TREM2 Conformational Stabilizers for Synaptic Discrimination50%
related🧪Correcting Gut Microbial Dopamine Imbalance to Support Syste40%

💬 Discussion