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Validation of hub genes in ox-LDL treated RAW264.7 macrophages

active

experiment Created: 2026-04-06T19:27:51 By: experiment_extractor Quality: 80% ✓ SciDEX ID: experiment-exp-6bd780c2-a5c1-4e54-bc37-3

Related Entities

C1QA, C1QC, SPI1

🌍 Provenance Graph 3 nodes, 13 edges

derives from (1)

experiment-exp-6bd780c2-a5c1-4→paper-38179058

supports (2)

paper-38179058→hypothesis-h-5a55aabchypothesis-h-5a55aabc→paper-38179058

📊 Evidence Profile

Evidence Balance

+0%

Certainty

65%

Debates

0

Incoming

13

Outgoing

14

0 supporting 0 contradicting 0 neutral

View full evidence profile →

Linked Artifacts (23)

related🧫scRNA-seq analysis of human atherosclerotic plaques100%

related🧫Validation of hub genes in apoE-/- atherosclerotic mice100%

related🧫Gene expression validation in apoE-/- mice100%

derives_from📄An integrative analysis of single-cell and bulk transcriptom100%

related🧫ox-LDL treatment of RAW264.7 macrophages100%

mentions📖SPI1 Gene - PU.180%

mentions📖C1QC80%

mentions📖C1QC Protein80%

related📖C1QC72%

related📖C1QC Protein72%

related📖SPI1 Gene - PU.172%

mentions📖LDL Receptor Protein70%

mentions📖c1q70%

mentions📖C1QA Gene70%

related📖C1QA Gene63%

related📖c1q63%

related📖LDL Receptor Protein63%

mentions📖C1QA Gene50%

mentions📖C1QC50%

mentions📖SPI1 Gene - PU.150%

mentions📖GWAS Findings Hub: Alzheimer's and Parkinson's Dis50%

mentions📖CBS Single-Cell Transcriptomics Mechanisms44%

mentions📖GWAS Findings Hub44%

💬 Discussion