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🧫

TRIM21-mediated K63-linked ubiquitination of G3BP1

experiment Created: 2026-04-04T12:25:10 By: experiment_extractor Quality: 95% ✓ SciDEX ID: experiment-exp-0732dce4-a7d4-4253-abdc-f
Related Entities
G3BP1
🌍 Provenance Graph 2 nodes, 1 edges

derives from (1)

📊 Evidence Profile
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
82
Outgoing
15
0 supporting 0 contradicting 0 neutral
View full evidence profile →
Linked Artifacts (90)
derives_from📄Stress granule homeostasis is modulated by TRIM21-mediated u100%
experiment_target📖G3BP1100%
mentions📖G3BP1100%
mentions📖G3BP190%
mentions📖G3BP1 Protein — Ras-GTPase-Activating Protein-Binding Protei70%
mentions📖G3BP170%
related📖G3BP1 Protein — Ras-GTPase-Activating Protein-Binding Protei63%
related📖G3BP163%
related🧪Stress Granule Phase Separation Modulators60%
related🧪Phase-Separated Organelle Targeting60%
related🧪RNA Granule Nucleation Site Modulation60%
related🧫G3BP1-mediated stress granule assembly via liquid-liquid pha60%
mentions📖Liquid-Liquid Phase Separation60%
mentions📖Ubiquitin60%
related🧪Liquid-Liquid Phase Separation Modifier Therapy60%
related🧫G3BP1 intrinsically disordered region analysis and phosphory60%
related🧫G3BP1-binding factor cooperativity in stress granule network60%
related📖Liquid-Liquid Phase Separation55%
related📖Liquid-Liquid Phase Separation54%
related📖Ubiquitin54%
mentions📖Stress Granule Dysfunction Hypothesis in Parkinson's Di50%
mentions📖Frontal and Temporal Lobe Selective Vulnerability in FTD — M50%
mentions📖Stress Granules in Neurodegeneration50%
mentions📖biomolecular-condensates-4r-tauopathies50%
mentions📖Tau vs TDP-43 Fate Switching in Frontotemporal Dementia50%
mentions📖Frontal Cortex Neurons in Frontotemporal Dementia50%
mentions📖Frontal Cortex Layer 2 Neurons in Frontotemporal Dementia50%
mentions📖RNA Granule Dysfunction in Neurodegeneration50%
mentions📖Stress Granule-Associated Neurons50%
mentions📖C9orf72→RNA/Dipeptide Repeat Pathology→ALS/FTD — Causal Chai50%
mentions📖Stress Granule Modulation Therapy50%
mentions📖TDP-43 RNA Granule Pathway50%
mentions📖Biomolecular Condensates in Neurodegeneration50%
mentions📖PSP Liquid-Liquid Phase Separation and Biomolecular Condensa50%
mentions📖Corticosteroids in FTD Trial50%
mentions📖Protein Phase Separation in Parkinson's Disease50%
mentions📖stress-granule-disease-comparison50%
mentions📖Stress Granule Formation in Neurodegeneration50%
mentions📖Stress Granule Dysfunction in 4R-Tauopathies50%
mentions📖RNA Metabolism in Alzheimer's Disease50%
mentions📖Stress Granules in Neurodegeneration50%
mentions📖Stress Granules and RNA Granules in Neurodegeneration50%
mentions📖LLPS Modulator Therapy50%
mentions📖Stress Granules and RNP Granules50%
mentions📖Oxidative Stress in Neurodegeneration50%
mentions📖Stress Granule Dysfunction Validation in Parkinson's Di50%
mentions📖MAPK Signaling Inhibitors: Investment Landscape Analysis50%
mentions📖Stress Granule Homeostasis in ALS/FTD50%
mentions📖Stress Granule Dynamics in Neurodegeneration50%
mentions📖Ferroptosis in Neurodegeneration50%
mentions📖Gabapentin ALS Trial44%
mentions📖Spinal Cord Motor Neurons in Amyotrophic Lateral Sclerosis44%
mentions📖Masitinib ALS Trial44%
mentions📖Motor Cortex in Amyotrophic Lateral Sclerosis44%
mentions📖High-Dose Vitamins ALS Trial44%
mentions📖Upper Motor Neurons in Amyotrophic Lateral Sclerosis44%
mentions📖Spinal Cord Neurons in Amyotrophic Lateral Sclerosis44%
mentions📖Idebenone ALS Trial44%
mentions📖RNA Metabolism Dysregulation in 4R-Tauopathies44%
mentions📖events44%
mentions📖Intravenous Immunoglobulin (IVIG) in ALS Trial44%
mentions📖amiloride-als44%
mentions📖Cortical GABAergic Interneurons in Amyotrophic Lateral Scler44%
mentions📖RNA Metabolism Dysregulation Pathway44%
mentions📖Oculomotor Neurons in Amyotrophic Lateral Sclerosis44%
mentions📖treatments44%
mentions📖Edaravone ALS Trial44%
mentions📖Lithium Continuation in ALS Trial44%
mentions📖Betz Cells in Amyotrophic Lateral Sclerosis44%
mentions📖Sargramostim (GM-CSF) ALS Trial44%
mentions📖ER Stress and UPR Modulator Therapy for Neurodegeneration44%
mentions📖Creatine ALS Trial44%
mentions📖RNA G-quadruplexes in Neurodegeneration44%
mentions📖Lithium Carbonate in Amyotrophic Lateral Sclerosis44%
mentions📖Low-Dose Naltrexone ALS Trial44%
mentions📖nimodipine-als44%
mentions📖CVN424 Phase 3 Trial for Parkinson's Disease44%
mentions📖SQSTM1/p6244%
mentions📖technologies44%
mentions📖Section 193 Advanced Integrated Cell Stress Response Therapy44%
mentions📖atl1103-antisense-als44%
mentions📖Tauraso (Nimodipine) ALS Trial44%
mentions📖Sodium Phenylbutyrate ALS Trial44%
mentions📖Neuroimmune Dysfunction in Frontotemporal Dementia44%
mentions📖Spinal Cord Motor Neurons in Amyotrophic Lateral Sclerosis44%
mentions📖D-Cycloserine ALS Trial44%
mentions📖viral-post-infectious-als44%
mentions📖ALS-FTD Overlap: Mechanistic Pathways44%
mentions📖Epigenetics in Amyotrophic Lateral Sclerosis44%
mentions📖Riluzole ALS Trials44%

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