Mitochondrial DNA-Driven AIM2 Inflammasome Activation in Neurodegeneration

h-var-d04a952932

## Mechanistic Overview Mitochondrial DNA-Driven AIM2 Inflammasome Activation in Neurodegeneration starts from the claim that modulating AIM2, CASP1, IL1B, PYCARD within the disease context of neurodegeneration can redirect a disease-relevant process. The original description reads: "**Molecular Mechanism and Rationale** The AIM2 (Absent in Melanoma 2) inflammasome represents a sophisticated cytos