Microglial AIM2 Inflammasome as the Primary Driver of TDP-43 Proteinopathy Neuroinflammation in ALS/FTD

h-var-a0933e666d

## Mechanistic Overview Microglial AIM2 Inflammasome as the Primary Driver of TDP-43 Proteinopathy Neuroinflammation in ALS/FTD starts from the claim that modulating AIM2, CASP1, IL1B, PYCARD, TARDBP within the disease context of neurodegeneration can redirect a disease-relevant process. The original description reads: "## Mechanistic Overview Microglial AIM2 Inflammasome as the Primary Driver of