| Prevalence | 3-6% of all parkinsonism cases (approximately 0.5-1 per 100,000) |
| Age of onset | Typically >65 years |
| Sex ratio | Male predominance (1.5-2:1) |
| Risk factors | Hypertension, diabetes, hyperlipidemia, smoking, prior stroke/transient ischemic attack[@reich2010] |
| Hypertension | Most significant risk factor |
| Diabetes mellitus | Contributes to small vessel disease |
| Hypercholesterolemia | Atherosclerosis |
| Smoking | Endothelial damage |
| Atrial fibrillation | Cardioembolic events |
| Previous stroke | Direct vascular injury |
| Bradykinesia | Prominent, often axial (trunk) > limbs |
| Rigidity | Axial (neck and trunk) > limb, "lead-pipe" quality |
| Databases | OMIMOrphanetClinicalTrialsPubMed |
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