| Gene Symbol | ent-gene-a90f5952 |
| VPS29 (29 kDa) | This subunit serves as an adapter that connects the cargo recognition module to VPS35. VPS29 has a metalloenzyme-like fold and may function as a structural scaffold and regulatory component. |
| Synaptic vesicle recycling | Retromer is essential for trafficking of synaptic vesicle proteins, maintaining the presynaptic vesicle pool. |
| Receptor signaling | Retromer regulates trafficking of neurotransmitter receptors (including glutamate and dopamine receptors), affecting synaptic plasticity. |
| Axonal transport | Retromer function supports long-range transport in axons and dendrites. |
| Lysosomal delivery | Retromer directs proteins to lysosomes for degradation when not recycled, essential for cellular clearance. |
| KG Connections | 7 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!