| Gene Symbol | ent-gene-c413dbdb |
| Neuronal development | Regulates neurogenesis, neuronal differentiation, and dendritic arborization[@hmmerle2003] |
| Synaptic plasticity | Modulates synaptic vesicle dynamics through synapsin I phosphorylation[@wenzel2009] |
| Learning and memory | Influences CREB-mediated gene expression critical for memory formation[@ahn2006] |
| Cell cycle regulation | Controls neuronal cell cycle exit and differentiation[@yabut2011] |
| Tau protein | DYRK1A phosphorylates tau at multiple sites (Thr212, Ser214, Ser262), promoting its aggregation and hyperphosphorylation[@woods2001] |
| [MAPT](/proteins/tau) gene expression | Regulates microtubule-associated protein tau (MAPT) expression[@yin2008] |
| APP phosphorylation | Enhances amyloid precursor protein (APP) processing toward amyloid-β production[@wen2010] |
| [BACE1](/entities/bace1) regulation | Upregulates β-secretase (BACE1) expression, increasing amyloidogenic processing[@hung2010] |
| Presenilin | Modulates γ-secretase activity through indirect mechanisms[@ryoo2008] |
| Synapsin I phosphorylation | Affects synaptic vesicle release dynamics[@wenzel2009a] |
| CREB phosphorylation | Alters synaptic plasticity and memory formation pathways[@ahn2006a] |
| KG Connections | 4 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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