protein 536 words KG: XRCC7PROTEIN
Contents

XRCC7 Protein (DNA-PKcs)

🔬 Protein Info
Gene SymbolXRCC7
Full NameX-Ray Repair Cross-Complementing 7 / DNA-PK Catalytic Subunit
AliasesDNA-PKcs
Chromosome8q24.21
Functionis a central component of the non-homologous end joining (NHEJ) pathway, the predominant mechanism for repairing DNA double-strand breaks (DSBs) in mammalian cells.
Primary Expressionvirtually all cell types:
Molecular Weight469 kDa
Amino Acids4128 aa
UniProt IDP78527
NCBI Gene ID5591
Ensembl IDENSG00000137413
OMIM604743
GeneCardsXRCC7
Human Protein AtlasXRCC7
N-terminal domainRegulatory and interaction surfaces
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

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