| Gene Symbol | WASF2 |
| Aliases | WASF2PROTEIN |
| Function | Wiskott-Aldrich Syndrome protein family member 2. |
| Subcellular Localization | - **ERK/MAPK**: Growth factor signaling modulates WASF2 phosphorylation - **Abl |
| Pathways | PI3K, MAPK |
| GeneCards | WASF2 |
| Human Protein Atlas | WASF2 |
| WHD (WASP Homology Domain) | Mediates protein-protein interactions |
| VCA Domain (Verprolin, Central, Acidic) | Activates Arp2/3 complex to promote actin nucleation |
| SHD (SCAR Homology Domain) | Interacts with other WAVE complex subunits (ABI1/2, HSPC300, NAP1, BRAC1) |
| Cell migration | Lamellipodia formation and membrane ruffling |
| Cytokinesis | Contractile ring assembly |
| Endocytosis | Vesicle trafficking and receptor internalization |
| Neuronal development | Growth cone dynamics and synapse formation |
| Rac1 | Primary GTPase activator of WAVE complex |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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