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protein 1,293 words KG: UBIQUILIN2
Contents

Ubiquilin-2 (UBQLN2)

🔬 Protein Info
Gene SymbolUBIQUILIN2
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight66 kDa
Amino Acids624 aa
GeneCardsUBIQUILIN2
Human Protein AtlasUBIQUILIN2
UBA domain (C-terminal)The ubiquitin-associated domain (residues 577–624) binds polyubiquitin chains on misfolded or damaged proteins, recognizing them as substrates for degradation [@ubiquilin2014].
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (4)

APOE-Dependent Autophagy Restoration
Score: 0.85Glycine-Rich Domain Competitive Inhibition
Score: 0.64Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62Liquid-Liquid Phase Separation Modifier Therapy
Score: 0.55

Related Analyses (2)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archivedCircuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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